Mimedx GS-5230 Dehydrated Human Amnion Chorion Membrane Allograft 6sq cm

Mimedx GS-5180 Dehydrated Human Amnion Chorion Membrane Allograft

Mimedx GS-5180

The GS‑5180 is an 18 mm circular disk of EPIFIX®, a dehydrated human amnion/chorion membrane produced using Mimedx’s proprietary PURION® process. Derived from donated placental tissue, this allograft retains a rich extracellular matrix composed of collagen types I, III, IV; elastin; fibronectin; laminin; proteoglycans—plus over 300 regulatory proteins like growth factors and cytokines that actively support wound healing and tissue regeneration. It undergoes terminal sterilization and is shelf‑stable at room temperature for up to five years, making it convenient for clinical use.

Clinically, this product is utilized in both acute and chronic wound environments, including diabetic foot ulcers, venous leg ulcers, pressure injuries, dehisced or surgical wounds, and even skin defects post-Mohs surgery. Level I evidence from randomized controlled trials has shown that EPIFIX significantly improves healing rates—achieving up to 85% closure at four weeks for diabetic ulcers versus standard care. Its benefits include providing a protective barrier, enhancing granulation tissue formation, and seamlessly integrating with adjunctive therapies like negative pressure wound therapy or hyperbaric oxygen. 

Understanding Mimedx Allograft

Mimedx GS-5180 is a dehydrated human amnion chorion membrane allograft that plays a significant role in regenerative medicine. This allograft is sourced from human placental tissue, and it contains important growth factors and proteins that encourage healing. When applied to wounds or surgical sites, it provides a natural framework that supports tissue regeneration and reduces inflammation. Unlike other treatment methods, this allograft offers a biocompatible solution for patients, making it an essential tool for medical professionals.

Benefits of Mimedx Allograft

There are numerous benefits to using the Mimedx GS-5180 dehydrated membrane allograft. Firstly, it helps promote faster healing and reduces scarring, which is crucial for patient recovery. Secondly, its unique composition allows it to adhere well to various tissues, providing a stable environment for regeneration. So, healthcare providers often choose Mimedx for various applications, such as orthopedic surgery, wound healing, and even dental procedures, because its versatility is well-established in clinical settings.

Clinical Applications and Considerations

Mimedx allografts are used in a wide range of clinical applications, including soft tissue reconstruction, dermatological procedures, and enhancing surgical repairs. However, it’s important to evaluate individual patient needs and medical history before utilizing this allograft. Medical professionals rely on the data supporting its effectiveness and safety in healing. Therefore, the Mimedx GS-5180 is not just a product; it’s part of an innovative approach to improving patient outcomes through advanced tissue management.